Pacs2^em1Huan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pacs2^em1Huan
• Name: phosphofurin acidic cluster sorting protein 2; endonuclease-mediated mutation 1, Lan Huang
• MGI ID: MGI:7571617
• Synonyms: Pacs2^flox
• Gene: Pacs2 Location: Chr12:112978128-113038021 bp, + strand Genetic Position: Chr12, 61.57 cM
• Alliance: Pacs2^em1Huan page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites within introns 1 and 3. (J:343974)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pacs2 Mutation: 28 strains or lines available

References

• Original: J:343974 Yang J, et al., Mitochondria-associated membrane protein PACS2 maintains right cardiac function in hypobaric hypoxia. iScience. 2023 Apr 21;26(4):106328
• All: 1 reference(s)