Npr3tm2(cre/ERT2)Hze
Targeted Allele Detail
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Symbol: |
Npr3tm2(cre/ERT2)Hze |
Name: |
natriuretic peptide receptor 3; targeted mutation 2, Hongkui Zeng |
MGI ID: |
MGI:7571411 |
Synonyms: |
Npr3-IRES2-CreERT2-neo |
Gene: |
Npr3 Location: Chr15:11839982-11907287 bp, - strand Genetic Position: Chr15, 5.83 cM
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Alliance: |
Npr3tm2(cre/ERT2)Hze page
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Mutation: |
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Insertion
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Npr3tm2(cre/ERT2)Hze expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Npr3 (MGI:97373) |
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Mutation details: The targeting vector contains, from 5' to 3', a partial Npr3 sequence spanning intron 6 up to and including the endogenous stop codon in exon 8 (also with a frt3 site in intron 7), an internal ribosome entry site 2 sequence (IRES2; allows translation initiation in the middle of an mRNA sequence), a cre/ERT2 gene, a bovine growth hormone polyA sequence, an AttB site, a PGK/gb2 promoter-Neomycin resistance gene-PGK polyA cassette, a frt5 site, an mRNA splice acceptor sequence, the 3' portion of the hygromycin gene (Hygro2) with SV40 polyA signal, and an AttP site.
(J:101977)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Npr3
(mouse)
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Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
All: |
1 reference(s) |
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