Phactr1^em1Tigm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Phactr1^em1Tigm
• Name: phosphatase and actin regulator 1; endonuclease-mediated mutation 1, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:7571328
• Synonyms: Phactr-1^Flox
• Gene: Phactr1 Location: Chr13:42834099-43292002 bp, + strand Genetic Position: Chr13, 21.05 cM
• Alliance: Phactr1^em1Tigm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 6 was flanked by loxP site via CRISPR/Cas9 technology. (J:341800)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phactr1 Mutation: 43 strains or lines available

References

• Original: J:341800 Rubin S, et al., PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic Arteriopathies in 3 Transgenic Mice. Arterioscler Thromb Vasc Biol. 2022 May;42(5):597-609
• All: 1 reference(s)