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Tg(Col6a1-TNFRSF1/GH1)1Gkl
Transgene Detail
Summary
Symbol: Tg(Col6a1-TNFRSF1/GH1)1Gkl
Name: transgene insertion 1, George Kollias
MGI ID: MGI:7571203
Synonyms: TgC6hp55
Transgene: Tg(Col6a1-TNFRSF1/GH1)1Gkl  Location: unknown  
Alliance: Tg(Col6a1-TNFRSF1/GH1)1Gkl page
Transgene
origin
Strain of Origin:  (C57BL/6J x CBA/J)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene contains a 1.5 kb fragment encompassing the human TNFR1 coding DNA sequence, downstream of the 7.5 kb 5-flanking region of the mouse collagen, type VI, alpha 1 promoter, followed by a 2.1 kb human GH1 minigene. The transgenic line carries 2 copies of the transgene. (J:332764)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:332764 Kaklamanos A, et al., Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression. Sci Rep. 2017 May 25;7(1):2397
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory