Tg(Col6a1-TNFRSF1/GH1)1Gkl
Transgene Detail
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| Symbol: |
Tg(Col6a1-TNFRSF1/GH1)1Gkl |
| Name: |
transgene insertion 1, George Kollias |
| MGI ID: |
MGI:7571203 |
| Synonyms: |
TgC6hp55 |
| Transgene: |
Tg(Col6a1-TNFRSF1/GH1)1Gkl Location: unknown
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| Alliance: |
Tg(Col6a1-TNFRSF1/GH1)1Gkl page
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| Strain of Origin: |
(C57BL/6J x CBA/J)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene contains a 1.5 kb fragment encompassing the human TNFR1 coding DNA sequence, downstream of the 7.5 kb 5-flanking region of the mouse collagen, type VI, alpha 1 promoter, followed by a 2.1 kb human GH1 minigene. The transgenic line carries 2 copies of the transgene.
(J:332764)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:332764 Kaklamanos A, et al., Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression. Sci Rep. 2017 May 25;7(1):2397 |
| All: |
1 reference(s) |
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