Slc12a2^em1Hsng
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc12a2^em1Hsng
• Name: solute carrier family 12, member 2; endonuclease-mediated mutation 1, Hongjun Song
• MGI ID: MGI:7570094
• Synonyms: Nkcc1^flox
• Gene: Slc12a2 Location: Chr18:58011750-58079893 bp, + strand Genetic Position: Chr18, 32.15 cM
• Alliance: Slc12a2^em1Hsng page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Guide RNAs were designed to insert loxP sites flanking exon 5 (140 bp). (J:342769)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc12a2 Mutation: 59 strains or lines available

References

• Original: J:342769 Zhang F, et al., Cell-autonomous and non-cell-autonomous roles of NKCC1 in regulating neural stem cell quiescence in the hippocampal dentate gyrus. Stem Cell Reports. 2023 Jul 11;18(7):1468-1481
• All: 1 reference(s)