Tg(HLA-DRA,HLA-DQB1)427Jmcc
Transgene Detail

Summary

• Symbol: Tg(HLA-DRA,HLA-DQB1)427Jmcc
• Name: transgene insertion 427, James McCluskey
• MGI ID: MGI:7569308
• Synonyms: Tg(HLA DR4-DQ8)427
• Transgene: Tg(HLA-DRA,HLA-DQB1)427Jmcc Location: unknown
• Alliance: Tg(HLA-DRA,HLA-DQB1)427Jmcc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• The transgene contains 2.2Mb YAC DNA clone with an intact region HLA DR4 - DQ3. (J:136840)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:136840 Chen Z, et al., Humanized transgenic mice expressing HLA DR4-DQ3 haplotype: reconstitution of phenotype and HLA-restricted T-cell responses. Tissue Antigens. 2006 Sep;68(3):210-9
• All: 2 reference(s)