Ago2^em1Jghy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ago2^em1Jghy
• Name: argonaute RISC catalytic subunit 2; endonuclease-mediated mutation 1, Jonathan G Hanley
• MGI ID: MGI:7567916
• Gene: Ago2 Location: Chr15:72967693-73056777 bp, - strand Genetic Position: Chr15, 33.92 cM
• Alliance: Ago2^em1Jghy page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting introduced the point mutation AGT (Ser) to GCT (Ala) responsible for the amino acid substitution of serine with alanine at position 388 (S388A). (J:82809)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ago2 Mutation: 54 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)