Mir125a^tm1.1Tat
Targeted Allele Detail

Summary

• Symbol: Mir125a^tm1.1Tat
• Name: microRNA 125a; targeted mutation 1.1, Naoya Tatsumi
• MGI ID: MGI:7565780
• Gene: Mir125a Location: Chr17:18051074-18051141 bp, + strand Genetic Position: Chr17, 10.5 cM
• Alliance: Mir125a^tm1.1Tat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260690
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129 x C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The coding region was replaced with a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:260690)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir125a Mutation: 5 strains or lines available

References

• Original: J:260690 Tatsumi N, et al., Deficiency in WT1-targeting microRNA-125a leads to myeloid malignancies and urogenital abnormalities. Oncogene. 2016 Feb 25;35(8):1003-14
• All: 1 reference(s)