Kdm5a^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Kdm5a^m1Btlr
• Name: lysine demethylase 5A; mutation 1, Bruce Beutler
• MGI ID: MGI:7565717
• Synonyms: Kdm5a^p.C322*, Kdm5a^Selbst
• Gene: Kdm5a Location: Chr6:120341085-120421535 bp, + strand Genetic Position: Chr6, 56.95 cM
• Alliance: Kdm5a^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced the mutation that results in the amino acid substitution of cysteine with a termination codon at position 322 (C322*). (J:300695)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm5a Mutation: 76 strains or lines available

References

• Original: J:300695 El Hayek L, et al., KDM5A mutations identified in autism spectrum disorder using forward genetics. Elife. 2020 Dec 22;9:e56883
• All: 1 reference(s)