Kdm5a^em1Btlr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kdm5a^em1Btlr
• Name: lysine demethylase 5A; endonuclease-mediated mutation 1, Bruce Beutler
• MGI ID: MGI:7565706
• Gene: Kdm5a Location: Chr6:120341085-120421535 bp, + strand Genetic Position: Chr6, 56.95 cM
• Alliance: Kdm5a^em1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 13 inserted 1 bp. Western blot analysis confirmed the absence of protein. (J:300695)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm5a Mutation: 76 strains or lines available

References

• Original: J:300695 El Hayek L, et al., KDM5A mutations identified in autism spectrum disorder using forward genetics. Elife. 2020 Dec 22;9:e56883
• All: 2 reference(s)