Mtm1^em1Flmg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mtm1^em1Flmg
• Name: X-linked myotubular myopathy gene 1; endonuclease-mediated mutation 1, Biomedical Sciences Research Center Al. Fleming
• MGI ID: MGI:7565590
• Gene: Mtm1 Location: ChrX:70254373-70359019 bp, + strand Genetic Position: ChrX, 36.55 cM
• Alliance: Mtm1^em1Flmg page

Mutation origin

• Strain of Origin: (CBA x C57BL/6)F1

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting introduced the mutation responsible for the amino acid substitution cysteine with serine at position 375 (C375S). (J:82809)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mtm1 Mutation: 28 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)