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Ern1em1Tac
Endonuclease-mediated Allele Detail
Summary
Symbol: Ern1em1Tac
Name: endoplasmic reticulum to nucleus signalling 1; endonuclease-mediated mutation 1, Taconic
MGI ID: MGI:7565583
Gene: Ern1  Location: Chr11:106285476-106378678 bp, - strand  Genetic Position: Chr11, 69.14 cM, cytoband E1
Alliance: Ern1em1Tac page
Mutation
origin
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Nucleotide substitutions
 
Mutation detailsCRISPR/Cas9 technology introduced single point mutation leading to the amino acid substitution of arginine with cysteine at position 594 (R594C). (J:82809)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ern1 Mutation:  58 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory