Clec2d^em1Xmj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Clec2d^em1Xmj
• Name: C-type lectin domain family 2, member d; endonuclease-mediated mutation 1, Xin-Ming Jia
• MGI ID: MGI:7563891
• Gene: Clec2d Location: Chr6:129157578-129163497 bp, + strand Genetic Position: Chr6, 63.16 cM, cytoband F3
• Alliance: Clec2d^em1Xmj page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 2 to 5. (J:326812)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec2d Mutation: 17 strains or lines available

References

• Original: J:326812 Li YN, et al., Inhibition of myeloid-derived suppressor cell arginase-1 production enhances T-cell-based immunotherapy against Cryptococcus neoformans infection. Nat Commun. 2022 Jul 14;13(1):4074
• All: 2 reference(s)