Ctnnd2^em1Kims
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ctnnd2^em1Kims
• Name: catenin delta 2; endonuclease-mediated mutation 1, Seonil Kim
• MGI ID: MGI:7563842
• Gene: Ctnnd2 Location: Chr15:30172739-31029487 bp, + strand Genetic Position: Chr15, 12.02 cM
• Alliance: Ctnnd2^em1Kims page

Mutation origin

• Strain of Origin: FVB

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology deleted exon 2 using sgRNAs 5-GAGGGGGGAGAGGTCCGTTCTGG-3 and 5-CTTCTTTAGGTGAACGTTGATGG-3. (J:342969)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctnnd2 Mutation: 65 strains or lines available

References

• Original: J:342969 Mendez-Vazquez H, et al., The autism-associated loss of delta-catenin functions disrupts social behavior. Proc Natl Acad Sci U S A. 2023 May 30;120(22):e2300773120
• All: 1 reference(s)