Cd226^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd226^em1Cya
• Name: CD226 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7562192
• Synonyms: CD226^fl
• Gene: Cd226 Location: Chr18:89195091-89290353 bp, + strand Genetic Position: Chr18, 59.05 cM
• Alliance: Cd226^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRIRSPR-targeting floxed exons 2 and 3. (J:296058, J:342876)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd226 Mutation: 35 strains or lines available

References

• Original: J:296058 Mu Y, et al., CD226 deficiency on regulatory T cells aggravates renal fibrosis via up-regulation of Th2 cytokines through miR-340. J Leukoc Biol. 2020 Apr;107(4):573-587
• All: 4 reference(s)