H19^tm1.1Pes
Targeted Allele Detail

Summary

• Symbol: H19^tm1.1Pes
• Name: H19, imprinted maternally expressed transcript; targeted mutation 1.1, Piroska E Szabo
• MGI ID: MGI:7562142
• Synonyms: H19^Ter
• Gene: H19 Location: Chr7:142129267-142131883 bp, - strand Genetic Position: Chr7, 87.97 cM
• Alliance: H19^tm1.1Pes page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:342873
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/SvImJ

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutation: Insertion
• Mutation details: A terminator cassette and floxed pgk-neo cassette were inserted upstream of the imprinting control region via homologous recombination. Cre mediated recombination removed the neo cassette. (J:342873)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H19 Mutation: 19 strains or lines available

References

• Original: J:342873 Liao J, et al., Establishment of paternal methylation imprint at the H19/Igf2 imprinting control region. Sci Adv. 2023 Sep 8;9(36):eadi2050
• All: 1 reference(s)