Gt(ROSA)26Sor^{em1(Cntnap1)Bhat}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(Cntnap1)Bhat}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Manzoor A Bhat
• MGI ID: MGI:7560698
• Synonyms: LSL-Cntnap1^Flag
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(Cntnap1)Bhat} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{em1(Cntnap1)Bhat} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cntnap1 (MGI:1858201)

• Mutation details: A loxP-flanked stop cassette and mouse Cntnap1 cDNA with a FLAG tag were inserted into the locus via CRISPR/Cas9 technology. (J:342323)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:342323 Chang C, et al., Mouse models of human CNTNAP1-associated congenital hypomyelinating neuropathy and genetic restoration of murine neurological deficits. Cell Rep. 2023 Oct 31;42(10):113274
• All: 1 reference(s)