Tpbg^tm1.2Suna
Targeted Allele Detail

Summary

• Symbol: Tpbg^tm1.2Suna
• Name: trophoblast glycoprotein; targeted mutation 1.2, Sunao Takeshita
• MGI ID: MGI:7560668
• Gene: Tpbg Location: Chr9:85724433-85729093 bp, + strand Genetic Position: Chr9, 46.4 cM
• Alliance: Tpbg^tm1.2Suna page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:342701
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The targeting construct floxed exon 2. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. Cre-mediated recombination removed exon 2. (J:342701)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tpbg Mutation: 21 strains or lines available

References

• Original: J:342701 Matsuoka K, et al., WAIF1 Is a Cell-Surface CTHRC1 Binding Protein Coupling Bone Resorption and Formation. J Bone Miner Res. 2018 Aug;33(8):1500-1512
• All: 1 reference(s)