Klf15^tm1.1Ogwa
Targeted Allele Detail

Summary

• Symbol: Klf15^tm1.1Ogwa
• Name: Kruppel-like transcription factor 15; targeted mutation 1.1, Wataru Ogawa
• MGI ID: MGI:7550408
• Gene: Klf15 Location: Chr6:90439558-90452220 bp, + strand
• Alliance: Klf15^tm1.1Ogwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:286898
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exon 2. Flp-mediated recombination removed the selection cassette inserted upstream of exon 2. (J:286898)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf15 Mutation: 21 strains or lines available

References

• Original: J:286898 Hirata Y, et al., Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis. JCI Insight. 2019 Feb 21;4(4)
• All: 3 reference(s)