Gt(ROSA)26Sor^{tm1(tTA,tetO-OVAL,-EGFP)Ddnd}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(tTA,tetO-OVAL,-EGFP)Ddnd}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, David G DeNardo
• MGI ID: MGI:7550403
• Synonyms: R26^tm1(LSL-OG)
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(tTA,tetO-OVAL,-EGFP)Ddnd} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:285844
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced a Tet-off regulation sequence with a floxed stop cassette, tTA, tetracycline response element, full-length chicken ovalbumin, IRES, and EGFP reporter gene. (J:285844)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:285844 Hegde S, et al., Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer. Cancer Cell. 2020 Mar 16;37(3):289-307.e9
• All: 2 reference(s)