Hmgcs2^em1Pchh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hmgcs2^em1Pchh
• Name: 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2; endonuclease-mediated mutation 1, Patrick CH Hsieh
• MGI ID: MGI:7550364
• Gene: Hmgcs2 Location: Chr3:98187751-98218054 bp, + strand Genetic Position: Chr3, 42.74 cM
• Alliance: Hmgcs2^em1Pchh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting flanked exon 2. (J:338123)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hmgcs2 Mutation: 36 strains or lines available

References

• Original: J:338123 Cheng YY, et al., Metabolic Changes Associated With Cardiomyocyte Dedifferentiation Enable Adult Mammalian Cardiac Regeneration. Circulation. 2022 Dec 20;146(25):1950-1967
• All: 1 reference(s)