Xirp2^em1Jshn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Xirp2^em1Jshn
• Name: xin actin-binding repeat containing 2; endonuclease-mediated mutation 1, Jung-Bum Shin
• MGI ID: MGI:7549455
• Synonyms: Xirp2^deltaLIM/CTD
• Gene: Xirp2 Location: Chr2:67276343-67356964 bp, + strand Genetic Position: Chr2, 39.31 cM
• Alliance: Xirp2^em1Jshn page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Single point mutation
• CRISPR-targeting generated a 1 bp substitution in exon 8, introducing a stop codon. (J:338149)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xirp2 Mutation: 163 strains or lines available

References

• Original: J:338149 Wagner EL, et al., Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain. Elife. 2023 Jun 9;12
• All: 1 reference(s)