Tagln3^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tagln3^em1(IMPC)J
• Name: transgelin 3; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7548782
• Gene: Tagln3 Location: Chr16:45531593-45544971 bp, - strand Genetic Position: Chr16, 29.99 cM
• Alliance: Tagln3^em1(IMPC)J page
• IMPC: Tagln3 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGATTCCCTGTGCTGCTTGG and TGATCTCCCATTCTTAATGG, which resulted in a 545 bp deletion beginning at Chromosome 16 position 45,722,809 bp and ending after 45,723,353 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000129242 (exon 2) and 370 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 60 and early stop 10 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tagln3 Mutation: 18 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)