Pkd1l1^em1Noh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pkd1l1^em1Noh
• Name: polycystic kidney disease 1 like 1; endonuclease-mediated mutation 1, Nobutaka Hirokawa
• MGI ID: MGI:7548770
• Synonyms: Pkd1l1^KikGR
• Gene: Pkd1l1 Location: Chr11:8782025-8924365 bp, - strand Genetic Position: Chr11, 5.57 cM, cytoband A2
• Alliance: Pkd1l1^em1Noh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting replaced the first ATG in exon 2 with a humanized monomeric KikGR1 reporter gene, linker, and BamHI sequence. (J:339246)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkd1l1 Mutation: 161 strains or lines available

References

• Original: J:339246 Tanaka Y, et al., Nodal flow transfers polycystin to determine mouse left-right asymmetry. Dev Cell. 2023 Aug 21;58(16):1447-1461.e6
• All: 1 reference(s)