Lncenc1^{tm1.1(NCC)Wcs}
Targeted Allele Detail

Summary

• Symbol: Lncenc1^{tm1.1(NCC)Wcs}
• Name: long non-coding RNA, embryonic stem cells expressed 1; targeted mutation 1.1, William C Skarnes
• MGI ID: MGI:7548750
• Gene: Lncenc1 Location: Chr13:97571441-97641366 bp, + strand Genetic Position: Chr13, 50.71 cM
• Alliance: Lncenc1^{tm1.1(NCC)Wcs} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:339418
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• The targeting construct floxed the first coding exon. Cre-mediated recombination removed exon 1. (J:339418)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lncenc1 Mutation: 67 strains or lines available

References

• Original: J:339418 Han Y, et al., A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage. Am J Physiol Lung Cell Mol Physiol. 2023 May 1;324(5):L584-L595
• All: 1 reference(s)