Tnf^em1Irc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tnf^em1Irc
• Name: tumor necrosis factor; endonuclease-mediated mutation 1, Inflammation Research Center
• MGI ID: MGI:7548540
• Synonyms: TNF^emARE
• Gene: Tnf Location: Chr17:35418357-35420983 bp, - strand Genetic Position: Chr17, 18.59 cM
• Alliance: Tnf^em1Irc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 107 bp in the 3'UTR. (J:339805)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnf Mutation: 48 strains or lines available

References

• Original: J:339805 Verboom L, et al., OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection. Cell Death Dis. 2023 Aug 19;14(8):534
• All: 1 reference(s)