Ncf1^em1Bga
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ncf1^em1Bga
• Name: neutrophil cytosolic factor 1; endonuclease-mediated mutation 1, Bin Gao
• MGI ID: MGI:7547361
• Gene: Ncf1 Location: Chr5:134248907-134258479 bp, - strand Genetic Position: Chr5, 74.47 cM
• Alliance: Ncf1^em1Bga page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 mediated recombination introduced loxP sites into introns 1 and 8. (J:342297)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ncf1 Mutation: 40 strains or lines available

References

• Original: J:342297 Ma J, et al., Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure. J Clin Invest. 2022 Jul 15;132(14):e157780
• All: 1 reference(s)