Diaph1^tm1.1Rrmy
Targeted Allele Detail

Summary

• Symbol: Diaph1^tm1.1Rrmy
• Name: diaphanous related formin 1; targeted mutation 1.1, Ravichandran Ramasamy
• MGI ID: MGI:7547173
• Synonyms: Diaph1^flox
• Gene: Diaph1 Location: Chr18:37976654-38068529 bp, - strand Genetic Position: Chr18, 19.71 cM
• Alliance: Diaph1^tm1.1Rrmy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:342222
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exons 4 through 7. Flp-mediated recombination removed the selection cassette inserted into intron 7. (J:342222)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Diaph1 Mutation: 116 strains or lines available

References

• Original: J:342222 Yepuri G, et al., DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress. Nat Commun. 2023 Oct 30;14(1):6900
• All: 1 reference(s)