Tmem201^em2Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmem201^em2Smoc
• Name: transmembrane protein 201; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7547167
• Gene: Tmem201 Location: Chr4:149799832-149822501 bp, - strand Genetic Position: Chr4, 80.15 cM
• Alliance: Tmem201^em2Smoc page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination created a 773 bp deletion and 3 bp insertion removing all of exon 7. (J:342229)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tmem201 Mutation: 25 strains or lines available

References

• Original: J:342229 Zhang Y, et al., Inner nuclear membrane protein TMEM201 maintains endothelial cell migration and angiogenesis by interacting with the LINC complex. J Mol Cell Biol. 2022 Jul 14;14(3)
• All: 1 reference(s)