Alkbh5^em1Shnh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Alkbh5^em1Shnh
• Name: alkB homolog 5, RNA demethylase; endonuclease-mediated mutation 1, Huiyong Shen
• MGI ID: MGI:7547015
• Synonyms: Alkbh5^fl
• Gene: Alkbh5 Location: Chr11:60428509-60449338 bp, + strand Genetic Position: Chr11, 37.81 cM
• Alliance: Alkbh5^em1Shnh page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 1. (J:340511)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alkbh5 Mutation: 21 strains or lines available

References

• Original: J:340511 Li Z, et al., The N(6)-methyladenosine demethylase ALKBH5 negatively regulates the osteogenic differentiation of mesenchymal stem cells through PRMT6. Cell Death Dis. 2021 Jun 4;12(6):578
• All: 2 reference(s)