Ptn^em3Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ptn^em3Smoc
• Name: pleiotrophin; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:7547013
• Synonyms: Ptn^{em1(flox)Smoc}
• Gene: Ptn Location: Chr6:36691863-36787114 bp, - strand Genetic Position: Chr6, 15.48 cM
• Alliance: Ptn^em3Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting produced a floxed allele. (J:340716)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptn Mutation: 17 strains or lines available

References

• Original: J:340716 Li H, et al., Pleiotrophin ameliorates age-induced adult hippocampal neurogenesis decline and cognitive dysfunction. Cell Rep. 2023 Aug 22;42(9):113022
• All: 1 reference(s)