Rbpms^{em1(cre/ERT2)Yzhe}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rbpms^{em1(cre/ERT2)Yzhe}
• Name: RNA binding protein gene with multiple splicing; endonuclease-mediated mutation 1, Yingfeng Zheng
• MGI ID: MGI:7547006
• Synonyms: RBPMSCreERT2, Rbpmsem1^{Cin (CreERT2-P2A)}
• Gene: Rbpms Location: Chr8:34272671-34419891 bp, - strand Genetic Position: Chr8, 20.85 cM
• Alliance: Rbpms^{em1(cre/ERT2)Yzhe} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Rbpms^{em1(cre/ERT2)Yzhe} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Rbpms (MGI:1334446)

• Mutation details: Using the CRISPR/Cas9 method, a CreERT2-P2A gene cassette was inserted between the Rbpms translation initiation site ATG and the first exon coding region. (J:342043)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Rbpms (mouse) Summary of all recombinase alleles driven by Rbpms. Comparative matrix view of recombinase activities Alliance mouse Rbpms gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbpms Mutation: 489 strains or lines available

References

• Original: J:342043 Li G, et al., The RBPMS(CreERT2-tdTomato) mouse line for studying retinal and vascular relevant diseases. iScience. 2023 Nov 17;26(11):108111
• All: 1 reference(s)