Bin1^tm1.1Jlpt
Targeted Allele Detail

Summary

• Symbol: Bin1^tm1.1Jlpt
• Name: bridging integrator 1; targeted mutation 1.1, Jocelyn Laporte
• MGI ID: MGI:7546815
• Gene: Bin1 Location: Chr18:32510283-32568790 bp, + strand Genetic Position: Chr18, 18.01 cM
• Alliance: Bin1^tm1.1Jlpt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:330841
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed exon 20 and inserted an FRT- and loxP-flanked neomycin resistance cassette. Cre-mediated recombination removed exon 20 and the selection cassette. (J:330841)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bin1 Mutation: 29 strains or lines available

References

• Original: J:330841 Li Q, et al., Dynamin-2 reduction rescues the skeletal myopathy of a SPEG-deficient mouse model. JCI Insight. 2022 Aug 8;7(15):e157336
• All: 1 reference(s)