Dnm2^tm1.1Jlpt
Targeted Allele Detail

Summary

• Symbol: Dnm2^tm1.1Jlpt
• Name: dynamin 2; targeted mutation 1.1, Jocelyn Laporte
• MGI ID: MGI:7546807
• Gene: Dnm2 Location: Chr9:21336204-21419055 bp, + strand Genetic Position: Chr9, 7.79 cM
• Alliance: Dnm2^tm1.1Jlpt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209721
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed exon 2 and inserted an FRT-flanked neomycin resistance cassette. Cre-mediated recombination removed the selection cassette. (J:209721)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnm2 Mutation: 101 strains or lines available

References

• Original: J:209721 Cowling BS, et al., Reducing dynamin 2 expression rescues X-linked centronuclear myopathy. J Clin Invest. 2014 Mar 3;124(3):1350-63
• All: 3 reference(s)