Stat2^em1Appsc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Stat2^em1Appsc
• Name: signal transducer and activator of transcription 2; endonuclease-mediated mutation 1, Applied StemCell
• MGI ID: MGI:7546783
• Synonyms: Stat2^fl
• Gene: Stat2 Location: Chr10:128106428-128128718 bp, + strand Genetic Position: Chr10, 76.5 cM
• Alliance: Stat2^em1Appsc page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Two LoxP sequences were inserted into intron 3 and intron 6 of the gene. (J:342113)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stat2 Mutation: 41 strains or lines available

References

• Original: J:342113 Chiriac MT, et al., IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling. Gut. 2023 Oct 26
• All: 1 reference(s)