Gtsf1^em1Pdz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gtsf1^em1Pdz
• Name: gametocyte specific factor 1; endonuclease-mediated mutation 1, Phillip Zamore
• MGI ID: MGI:7545675
• Synonyms: Gtsf1^em1(Flag)Pdz
• Gene: Gtsf1 Location: Chr15:103310885-103338872 bp, - strand Genetic Position: Chr15, 58.93 cM, cytoband F3
• Alliance: Gtsf1^em1Pdz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-targeting introduced a triple FLAG tag and HA tag into the locus. (J:341525)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gtsf1 Mutation: 19 strains or lines available

References

• Original: J:341525 Arif A, et al., GTSF1 accelerates target RNA cleavage by PIWI-clade Argonaute proteins. Nature. 2022 Aug;608(7923):618-625
• All: 1 reference(s)