Del(2Pirnac2-Gm13817)1Pdz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(2Pirnac2-Gm13817)1Pdz
• Name: deletion, Chr 2, Phillip Zamore 1
• MGI ID: MGI:7545672
• Synonyms: pi2^em1Pdz
• Gene: Del(2Pirnac2-Gm13817)1Pdz Location: unknown Genetic Position: Chr2, Syntenic

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Del(2Pirnac2-Gm13817)1Pdz involves 2 genes/genome features (Pirnac2, Gm13817) View all
• Mutation details: CRISPR-targeting removed the piRNA cluster located on chromosome 2 and a portion of the GM13817 promoter (chr2:92539403-92542146, mm10). (J:341526)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Del(2Pirnac2-Gm13817)1Pdz Mutation: 1 strain or line available

References

• Original: J:341526 Gainetdinov I, et al., Relaxed targeting rules help PIWI proteins silence transposons. Nature. 2023 Jul;619(7969):394-402
• All: 2 reference(s)