Areg^em1Hkj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Areg^em1Hkj
• Name: amphiregulin; endonuclease-mediated mutation 1, Keiji Hirota
• MGI ID: MGI:7545589
• Synonyms: Areg^fl
• Gene: Areg Location: Chr5:91287458-91296291 bp, + strand Genetic Position: Chr5, 44.78 cM
• Alliance: Areg^em1Hkj page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 3 and 4. (J:341797)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Areg Mutation: 33 strains or lines available

References

• Original: J:341797 Ikeno Y, et al., Foxp3+ Regulatory T Cells Inhibit CCl4-Induced Liver Inflammation and Fibrosis by Regulating Tissue Cellular Immunity. Front Immunol. 2020;11:584048
• All: 1 reference(s)