Naprt^em1Himo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Naprt^em1Himo
• Name: nicotinate phosphoribosyltransferase; endonuclease-mediated mutation 1, Hisashi Mori
• MGI ID: MGI:7544008
• Gene: Naprt Location: Chr15:75762812-75766330 bp, - strand Genetic Position: Chr15, 35.05 cM
• Alliance: Naprt^em1Himo page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting of exon 2 generated a null allele. (J:334708)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Naprt Mutation: 17 strains or lines available

References

• Original: J:334708 Yaku K, et al., BST1 regulates nicotinamide riboside metabolism via its glycohydrolase and base-exchange activities. Nat Commun. 2021 Nov 19;12(1):6767
• All: 2 reference(s)