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Nos2em1Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Nos2em1Smoc
Name: nitric oxide synthase 2, inducible; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:7543918
Synonyms: Mcm8-
Gene: Nos2  Location: Chr11:78811613-78851052 bp, + strand  Genetic Position: Chr11, 46.74 cM
Alliance: Nos2em1Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    Exon12-13 of Nos2 gene were deleted to generate Nos2 knockout mice. (J:238766)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nos2 Mutation:  67 strains or lines available
References
Original:  J:341798 Lin M, et al., MCM8-mediated mitophagy protects vascular health in response to nitric oxide signaling in a mouse model of Kawasaki disease. Nat Cardiovasc Res. 2023;2(8):778-792
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory