Scml4^em2Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Scml4^em2Smoc
• Name: Scm polycomb group protein like 4; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7543796
• Synonyms: Scml4^{em1(flox)Smoc}
• Gene: Scml4 Location: Chr10:42736366-42836776 bp, + strand Genetic Position: Chr10, 22.89 cM
• Alliance: Scml4^em2Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 mediated recombination inserted loxP sites around at least one exon. (J:341490)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Scml4 Mutation: 21 strains or lines available

References

• Original: J:341490 Feng M, et al., Fatty Acids Support the Fitness and Functionality of Tumor-Resident CD8+ T Cells by Maintaining SCML4 Expression. Cancer Res. 2023 Oct 13;83(20):3368-3384
• All: 1 reference(s)