Pdcd1^em1Jwji
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pdcd1^em1Jwji
• Name: programmed cell death 1; endonuclease-mediated mutation 1, Jianwei Jiao
• MGI ID: MGI:7543761
• Synonyms: Pd1^fl
• Gene: Pdcd1 Location: Chr1:93966027-93980278 bp, - strand Genetic Position: Chr1, 47.47 cM
• Alliance: Pdcd1^em1Jwji page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 mediated recombination using 2 guide RNAs inserted loxP sites around a genomic region including exons 2 to 4. (J:341690)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd1 Mutation: 97 strains or lines available

References

• Original: J:341690 Ji F, et al., Brain-specific Pd1 deficiency leads to cortical neurogenesis defects and depressive-like behaviors in mice. Cell Death Differ. 2023 Sep;30(9):2053-2065
• All: 1 reference(s)