Nfe2l2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nfe2l2^em1Cya
• Name: nuclear factor, erythroid derived 2, like 2; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7543603
• Synonyms: Nrf2^-
• Gene: Nfe2l2 Location: Chr2:75505857-75534985 bp, - strand Genetic Position: Chr2, 44.75 cM
• Alliance: Nfe2l2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a knock-out allele. (J:341727)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nfe2l2 Mutation: 94 strains or lines available

References

• Original: J:341727 Han P, et al., Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice. Free Radic Biol Med. 2022 Oct 27;193(Pt 1):421-429
• All: 3 reference(s)