Ephx2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ephx2^em1Cya
• Name: epoxide hydrolase 2, cytoplasmic; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7543434
• Synonyms: sEH^-
• Gene: Ephx2 Location: Chr14:66321823-66361949 bp, - strand Genetic Position: Chr14, 34.36 cM, cytoband D
• Alliance: Ephx2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a knock-out allele. (J:341695)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ephx2 Mutation: 41 strains or lines available

References

• Original: J:341695 Zhang J, et al., Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury. Int J Biol Sci. 2023;19(1):294-310
• All: 1 reference(s)