Efnb2^{em1(cre/ERT2)Kloh}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Efnb2^{em1(cre/ERT2)Kloh}
• Name: ephrin B2; endonuclease-mediated mutation 1, Kyle Loh
• MGI ID: MGI:7543314
• Gene: Efnb2 Location: Chr8:8667434-8711242 bp, - strand Genetic Position: Chr8, 3.42 cM
• Alliance: Efnb2^{em1(cre/ERT2)Kloh} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Efnb2^{em1(cre/ERT2)Kloh} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Efnb2 (MGI:105097)

• Mutation details: CRISPR/cas9 genome editing was used to replace the stop codon of the Efnb2 gene on chromosome 8 with a cassette encoding a GSG-P2A linker, followed by a CreERT2 fusion protein, and a single F5 site. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Efnb2 (mouse) Summary of all recombinase alleles driven by Efnb2. Alliance mouse Efnb2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Efnb2 Mutation: 28 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)