Il3ra^em1Neur
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il3ra^em1Neur
• Name: interleukin 3 receptor, alpha chain; endonuclease-mediated mutation 1, Markus F Neurath
• MGI ID: MGI:7541364
• Gene: Il3ra Location: Chr14:8114270-8123851 bp, - strand Genetic Position: Chr14, 7.08 cM
• Alliance: Il3ra^em1Neur page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination created a deletion spanning exon 3. (J:341590)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il3ra Mutation: 37 strains or lines available

References

• Original: J:341590 Ullrich KA, et al., IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells. Gut. 2023 Aug 4
• All: 1 reference(s)