B3galt5^em2Ktak
Endonuclease-mediated Allele Detail

Summary

• Symbol: B3galt5^em2Ktak
• Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5; endonuclease-mediated mutation 2, Kiyoshi Takeda
• MGI ID: MGI:7539756
• Synonyms: B3galt5^D116A
• Gene: B3galt5 Location: Chr16:96037001-96121059 bp, + strand Genetic Position: Chr16, 56.88 cM
• Alliance: B3galt5^em2Ktak page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting introduced the mutation responsible for the amino acid substitution of aspartic acid with alanine at position 116 (D116A). (J:341473)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any B3galt5 Mutation: 12 strains or lines available

References

• Original: J:341473 Taniguchi M, et al., Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon. Mucosal Immunol. 2023 Jul 13
• All: 1 reference(s)