Zbtb7b^tm4Tani
Targeted Allele Detail

Summary

• Symbol: Zbtb7b^tm4Tani
• Name: zinc finger and BTB domain containing 7B; targeted mutation 4, Ichiro Taniuchi
• MGI ID: MGI:7539430
• Synonyms: Thpok^{gfp:deltaTESPE}
• Gene: Zbtb7b Location: Chr3:89284953-89300976 bp, - strand Genetic Position: Chr3, 39.09 cM, cytoband A1-A2
• Alliance: Zbtb7b^tm4Tani page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254770
• Parent Cell Line: M1/M-1 (ES Cell)
• Strain of Origin: (129 x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The TE/Sth and PE regions were sequentially removed in the modified allele contained within the ES cells in which the coding region had been replaced with GFP. ES cells used contained Zbtb7b^tm1Tani. (J:254770)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb7b Mutation: 26 strains or lines available

References

• Original: J:254770 Kojo S, et al., Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes. Nat Commun. 2017 Sep 26;8(1):702
• All: 1 reference(s)