Ercc6l^em1Smyi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ercc6l^em1Smyi
• Name: excision repair cross-complementing rodent repair deficiency complementation group 6 like; endonuclease-mediated mutation 1, Songmin Ying
• MGI ID: MGI:7539425
• Synonyms: Pich^-
• Gene: Ercc6l Location: ChrX:101186426-101200697 bp, - strand Genetic Position: ChrX, 45.16 cM
• Alliance: Ercc6l^em1Smyi page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TALEN technology generated a 10 bp deletion from the beginning of exon 2. Western blot analysis confirmed absence of protein from whole tissue protein extracts from homozygotes. (J:339248)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ercc6l Mutation: 6 strains or lines available

References

• Original: J:339248 Geng X, et al., PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response. Adv Sci (Weinh). 2022 Mar;9(7):e2103837
• All: 1 reference(s)