Nsd1^em1Zmcai
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nsd1^em1Zmcai
• Name: nuclear receptor-binding SET-domain protein 1; endonuclease-mediated mutation 1, Zhenming Cai
• MGI ID: MGI:7539169
• Synonyms: NSD1^fl
• Gene: Nsd1 Location: Chr13:55357595-55466138 bp, + strand Genetic Position: Chr13, 29.8 cM
• Alliance: Nsd1^em1Zmcai page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exons 6 through 8. (J:337560)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nsd1 Mutation: 280 strains or lines available

References

• Original: J:337560 Zhai S, et al., H3K36 methyltransferase NSD1 is essential for normal B1 and B2 cell development and germinal center formation. Front Immunol. 2022;13:959021
• All: 1 reference(s)